Recent research has shown that an endothelial-specific glycocalyx component, endomucin (EMCN), is highly expressed in the glomerular endothelium and plays a key role supporting the normal structure and function of the glomerular filtration barrier by maintaining the tight junctions, homeostasis of the glomerular endothelium, and function of podocytes (81)
Topical application directly supports collagen and elastin production within the skin
This upregulation enhances resting energy expenditure and promotes the oxidation of adipose tissue
Reported benefits (per available research): Studied in animal (rodent) models for tendon, ligament, and muscle healing, with researchers attributing effects to promotion of angiogenesis and fibroblast activity (preclinical studies from a Croatian research group at the University of Zagreb, spanning several decades) Originally investigated for gastroprotective properties
Basic & clinical pharmacology & toxicology
[DOI] [PubMed] [Google Scholar] 265.Keremi B., Lohinai Z., Komora P., Duhaj S., Borsi K., Jobbagy-Ovari G., Kallo K., Szekely A.D., Fazekas A., Dobo-Nagy C., et al
