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PLoS ONE 10 , e0123454
For each eligible study, two authors (MM and AN) independently extracted data, which was then reviewed by a third author (JV) using a piloted spreadsheet, in accordance with Cochrane Collaboration guidelines (Higgins and Green, 2008)
Its renowned for its regenerative properties and ability to accelerate healing
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The cycle is energy-dependent since ATP is consumed in the synthesis of glutamine from glutamate: glutamate + ATP + NH3 glutamine + ADP + phosphate + 17 kJ/mol
Degenerative joint conditions are common as we age
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