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use tolerant varieties if available

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( For references see end of Chapter VIII ) REHANDLING AND FERMENTATION OF TOBACCO LEAF PRIOR TO MANUFACTURE Selection of leaf

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Susceptibility to Agrobacterium: Tobacco plants are naturally susceptible to Agrobacterium tumefaciens infection, making them an ideal host for Agrobacterium-mediated genetic transformation, which is a widely used method for introducing foreign genes into plant cells