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[2] [3] In October 2023, the MHRA also approved tirzepatide (Mounjaro) for weight management in adults with an initial BMI of at least 30 kg/m (obesity), or from 27 kg/m to less than 30 kg/m (overweight) in the presence of at least one weight-related comorbidity

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Studies have examined ipamorelin in models of lean mass accretion, visceral fat reduction, and metabolic syndrome, with findings consistent with the broader GH/IGF-1 axis literature