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Using a previously reported prevalence of e-cigarette use among the Saudi population of 26% 19 , the minimum required sample of 295 participants would be adequate in order to attain 95% confidence interval and 5% margin of error

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A second hypothesis is that chronic (round the clock) exposure of beta-2 receptors to long-acting beta-2 agonists results in the development of desensitization (tolerance) to all beta-2 agonists

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in 1969, sales dramatically increased and solidified the brand as an iconic staple in cellars around the world