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The threefold range of values observed in the moist snuff samples (Table 1) may well reflect differences in tobacco production practices between different manufacturers, as well as possible sample age at the time of analysis

A researcher reported a 45% increase mortality rate from cancer per 100,000 people from 1900 to 1924 and: The increase in the reported mortality rate of malignant disease has been so obvious in late years as to attract considerable popular attention, and to cause much alarm especially to the lay public

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JAMA Netw Open 2019 Oct 2;2(10)