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They found that E-cigarettes produce some ultrafine particles that can be harmful if exposed for long enough

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For example, inhibition of HDACs can increase the expression of key genes involved in memory processes, which are regulated by the cAMP response element-binding protein (CREB)-CREB-binding protein transcriptional complex (89)

24 May 2016 Hi Rj, Thanks for your comment

This approach is inherently subject to potential recall bias, reporting bias, and misclassification in both exposure (product use and intensity) and outcomes (adverse events)

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