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Stimulation of nicotinic acetylcholine receptors (nAChRs) after exposure to nicotine using minipumps for 2 weeks at dose of 0.125 mg/kg (s.c.) or microinjection of nicotine into the ventral tegmental area (VTA) caused changes in dopamine neurotransmission in male SpragueDawley rats and male Wistar rats, respectively (Fuxe et al., 1990

The net fiscal effect of these two potential impacts of the measure is highly uncertain

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Sometimes can fill a room, but then disappear