Children presenting neurological signs or symptoms, those unable to take oral medication, individuals with known malabsorption syndromes, infants under 6 months old, and patients using medications that may interfere with vitamin B12 absorption are typically treated with a parenteral protocol (1)
Because the follow-up time was fairly short, these results may have been caused by reverse causality, where a developing, undiagnosed condition was influencing IGF-1 levels at the time when the samples were taken
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Adult *AB liver was removed and fixed for identical tissue processing (Gupta and Mullins, Drug treatments Neomycin (10 mg/mL) and gentamicin (50 mg/mL) solutions (Sigma-Aldrich