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Generally, donors have to: Be generally well and fit Be 17 years or older Have enough blood to donate safely Live within specified miles Have proof of identity (Photo ID) and physical address Pass a basic physical exam Pass a primary health screen, blood test, and viral test (ex: HIV and hepatitis test) Things to Keep in Mind Before Donating Plasma Heres what you should remember about plasma donation: Before Your Plasma Donation Drink lots of water Do not smoke tobacco for an hour before donating Eat a healthy meal within two hours of your visit Avoid foods high in cholesterol or fat Avoid caffeine and alcohol before and on your donation day