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The good feeling that it brings usually leaves smokers resorting to it as a solution to their physical, emotional, and mental challenges

Several recent studies have documented a relationship between mental illness and smoking among adults and adolescents (Black et al

This analysis of drug harms in Canada found that alcohol causes the most harm overall Alcohol was followed by tobacco, nonprescription opioids (like fentanyl), cocaine, methamphetamine, and cannabis. Tobacco ranked first in 4 of the 16 harm categories: drug-related mortality, drug-specific damage to physical health, dependence, and environmental damage, the researchers wrote

For example, bupropion, which is also often prescribed to treat depression, Similarly, varenicline can cause insomnia and vivid dreams, among other side effects

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