chemicals found in cigarette smoke Cigarettes and Tobacco: What's Burning? DYK? Cigarette smoke contains more

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Tobacco kills more than 480,000 people annually, more than AIDS, alcohol, car accidents, illegal drugs, murders, and suicides combined 1

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Its validity may be due to the inclusion of the time-to-first-cigarette in the morning (TTFC) item, which appears to be especially strongly associated with relapse likelihood 16,17,18 and may be an especially informative measure of heritability of ND 19