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g , Enrichment of EGFR p.L858R hotspot driver mutations in SBS4-positive tumours from never-smokers compared to smokers using multivariable logistic regressions considering clinical and epidemiological covariates, including age, sex, genetic ancestry, histology, and tumour purity ( n = 5 mutated non-smoker cases, n = 1 mutated smoker case, n = 51 non-smoker wild-type cases, n = 301 smoker wild-type tumours)

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Refraining from a dosage increase causes extremely unpleasant feelings of irritability and anxiety

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