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The downregulation of PRKN in lung epithelial cells of COPD patients may contribute to the deficiency in mitophagy observed in these patients, leading to the accumulation of aberrant mitochondria and increased oxidative stress within cells (Ito et al., 2015)

Joining a support group is a great idea, too, whether it's through an organization like the American Cancer Society, a local support group, or an online community

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Smoking is one of the leading causes of this condition