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Therefore, SII in this context may partly function as a marker of the overall inflammatory burden, which is heightened by smoking but also influenced by other factors

See the Frogeye Leaf Spot of Tobacco factsheet for more information

Smoking related deaths made up 16% of all deaths across the UK in 2016 and smoking is the largest cause of preventable death in England

However, quitting can substantially reduce that risk, especially for those who quit at younger ages

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