The cumulative legacy of borderland residency had produced a population ill-suited to urban life, a noticeable unwillingness to settle down in one spot in preference to long-term homesteading (as did the Germans), and agricultural practices which quickly exhausted the soil, prompting hyper-residential mobility
#9 Maybe they had plan to sell the blend
Another possibility for the mechanism through which current smokers may have different bacteria community may be related to impaired antimicrobial defenses due to the immunosuppressive nature of tobacco
Some of that, of course, is caused by their legality, which makes them more accessible and more widely used
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