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One consequence is the doubling of the world population over the next few centuries as nutrition and food production improved

Native peoples had been growing it for medicinal and ritual purposes for centuries before European contact, smoking it in pipes or powdering it to use as snuff

Archived from the original (PDF) on June 16, 2010

It refers to the compulsive consumption of tobacco products, such as cigarettes, smokeless tobacco, or chewing tobacco, driven by cravings and withdrawal symptoms when not using

Communicable diseases of Old World origin resulted in an 80 to 95 percent reduction in the Indigenous population of the Americas from the 15th century onwards, and their near extinction in the Caribbean