The World Health Organization has denounced tobacco as one of the biggest public health threats in the world, killing more than 8 million people a year.

(10 July 2006), "The Association Between Marijuana Smoking and Lung Cancer", Archives of Internal Medicine , 166 (13): 13591367, doi:10.1001/archinte.166.13.1359, PMID 16832000, S2CID 10117687 Chemicals known to the state to cause cancer or reproductive toxicity (PDF), ca.gov, 20 July 2012, archived from the original (PDF) on 20 January 2013, retrieved 8 January 2013 Evidence on the carcinogenicity of marijuana smoke (PDF), Reproductive and Cancer Hazard Assessment Branch Office of Environmental Health Hazard Assessment, California Environmental Protection Agency, archived (PDF) from the original on 24 July 2012, retrieved 23 June 2012 The impact of cannabis on your lungs , British Lung Association, June 2012, archived from the original on 27 September 2013, retrieved 9 January 2013 "Medical consequences of marijuana use: a review of current literature"

Excavations near Koblenz in northern Germany turn up a Neanderthal skullcap, estimated at 170,000 years old, that was apparently used as a bowl
The economic burden of prescription opioid overdose, abuse, and dependence in the United States, 2013
Non-cigarette smoking tobacco and smokeless tobacco are taxed 32% of the wholesale price.6,7 Clean indoor air ordinances Smoking is prohibited in all government workplaces, private workplaces, schools, childcare facilities, restaurants, bars (except in cigar bars), retail stores and recreational/cultural facilities.7 Smoking restrictions are required in casinos/gaming establishments (tribal establishments are exempt).7 The use of e-cigarettes is prohibited in the states Third Judicial Circuit Court, on streetcars and street railway stations, and on child care center property and in homes and vehicles used to transport children in care when in operation for child care.9 Licensing laws Wholesalers are required to obtain a license to sell tobacco products
Back in the nineteen sixties and seventies, the Netherlands mainly had access to hash, which is not suited for smoking in a reefer, spliff or joint without tobacco