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Smoking devices often become warm or hot during use, and these conditions can affect pathogen survival

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Furthermore, silencing of NLRP3 dampened the ability of nicotine to induce HAECs pyroptosis, as evidenced by the decreases in the number of TUNEL and caspase-1 double-positive cells (Fig

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According to ICMR, E-Cigarette use adversely affects the cardiovascular system, impairs respiratory immune cell function and airways in a way similar to cigarette smoking and is responsible for severe respiratory disease