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[54] The inhaled substances trigger chemical reactions in nerve endings in the brain due to being similar to naturally occurring substances such as endorphins and dopamine, which are associated with sensations of pleasure

A study published in the Journal of the American Medical Association (JAMA) found that quitting smoking before age 44 years was associated with a reduction in mortality that was 21% higher than that associated with never smoking, and this was consistent across all sociodemographic groups studied 4

When electronic cigarettes and vapes came on the scene, it was no different

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