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Ex-drinkers and ex-smokers were subjects who had abstained from any type of drinking or smoking for at least 12 months

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Therefore, 1-(5'-phosphoribosyl)-5-formamido-4-imidazolecarboxamide was associated with purine metabolism, 1-methylxanthine was associated with caffeine metabolism, 1,2-dihydroxy-3-keto-5-methylthiopentene was involved in cysteine and methionine metabolism, 11-dehydro-thromboxane B2 was related to arachidonic acid metabolism, and 2-hydroxyethanesulfonate was involved in taurine and hypotaurine metabolism

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