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Most clients were connected through 211 referrals and were predominantly White/non-Hispanic females aged 25-44

Cigarette use alone, results in an estimated 430,000 deaths each year in the U.S., including 28,600 deaths in Florida

Subsequently, various chemokines and growth factors refined by activated endothelial cells and macrophages act on adjacent smooth muscle cells (or their precursor 12), inducing their proliferation and synthesis of extracellular matrix components in the intimal compartment, resulting in fibromuscular plaques [104]

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