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Additionally, the U.S

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A higher number of female ST users resided in higher age groups (43% of female ST users aged 55 years)

Participants who consumed the higher-potency cannabis also waited longer before drinking: 33.4 minutes, on average, compared to 22.5 minutes in the placebo group

Timeline of nicotine addiction development: Week 1-2: Initial tolerance begins forming Week 3-4: Physical dependence may emerge Month 2-3: Withdrawal symptoms appear between uses Month 3+: Full addiction often established in adolescents Cravings can occur within 30 minutes of last use THC addiction, while often underestimated, represents a genuine risk especially with high-potency vape products

Written informed consent was obtained from each participant prior to their inclusion in the study