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In the West, its always going to be in the context of getting out of your head

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Thats because the method of delivery is very different, and even an equivalent amount of nicotine will not give the same kick when delivered in vape versus a cigarette

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3.1 Endothelial dysfunction Various clinical and laboratory studies have shown that endothelial dysfunction induced by cigarette smoke is mediated by decreased nitric oxide (NO) bioavailability, increased production of superoxide anions, and increased production and release of endothelin ( 28 )

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