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As the growing scientific knowledge in the 1950s and 1960s led to increased awareness of the serious health effects of smoking, tobacco companies started promoting products aimed at reducing perceptions of risk [13], such as filtered and low-tar cigarettes [14]

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Key product details Product Esse Golden Leaf Availability In stock Category Cigarette SKU U63_33 Listed price 210.00 Before you order Check the pack format, flavour or variant, manufacturer details and the statutory warning printed on the sealed pack

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With that patented strain, 22nd Century subsequently created a series of very low nicotine content cigarette products called SPECTRUM that were exclusively provided to academic research institutions for use in clinical studies to assess the physiological and psychological effects of nicotine reduction in heavy smokers