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Most of the decline in usage was in the e-cigarette category, while other combustible tobacco products also saw significant decreases
doi:10.1016/j.oooo.2019.12.007 62
This suggests that smoking does not induce detectable genetic mutations in these mitochondrial genes but may contribute to epigenetic alterations affecting sperm function
moreover, it increases the cardiac rhythm and the pressure and contributes to the forming of thrombosis and atherosclerosis in the smokers

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