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Since 2019, the CDC Foundation and its partnersthe Centers for Disease Control and Prevention (CDC) and Truth Initiativehave conducted research on the impact of statewide flavored tobacco restrictions on sales of tobacco products, e-cigarette use by young people, and the effectiveness of flavored e-cigarette restriction policies, with the goal of keeping children and teens from accessing these addictive products

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Researchers found that cigarette use was also associated with CLCC initiation and use, but saw no significant variation between flavored and unflavored CLCC use

KarlssonJ.FullerR.1999Pharmacological regulation of the cough reflex- from experimental models to antitussive effects in man

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This suggests considerable contributions from environmental risk factors