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Furthermore, because they do not involve combustion or produce an aerosol cloud like E-cigarettes, nicotine pouches do not generate sidestream emissions, thus posing no secondhand exposure risk to bystanders

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It typically refers to situations when smokers use cigarettes, cigars, pipes and other tobacco products

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Substances in the CSE derived from both HTPs and traditional tobacco increased intracellular Ca 2+ concentration in OSCC cells Intracellular Ca 2+ , a ubiquitous second messenger, is vital in regulating numerous cellular processes, such as proliferation, apoptosis and cell migration, including in cancer cells [13]