the US EPA still does not know much about the health effects of poor water quality, noting that factors that can influence whether a contaminant will lead to health effects include the type of contaminant, its concentration in the water, individual susceptibility, the amount of water consumed, and the duration of exposure (2020)
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Resveratrol significantly reduced lipid peroxidation, restored glutathione balance, and attenuated astrocyte and microglial reactivity, indicating a protective effect against PPA-induced oxidative and inflammatory damage (Bhandari and Kuhad, 2017)
These cells no longer function properly but refuse to die, causing inflammation and accelerating aging