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VDAC was postulated to interact with 7-nAChR (the isoform considered to be the most abundant in the mitochondrial membrane), which implies the involvement of 7-nAChR in mitochondria-driven apoptosis due to high calcium exposure (Gergalova et al
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110 Extending research linking exposure to point-of-sale marketing with cigarette smoking among young people, research in Scotland also found that living in an area of high tobacco retail density predicted intention to try electronic cigarettes among adolescents
It also contributes to cancers of the head and neck, stomach, kidney, pancreas, colon, bladder, cervix, and can also cause leukemia