Unlike many other vitamins, B12 is stored in the liver in substantial quantities, meaning deficiency typically develops gradually over months to years as these reserves become depleted
Here is the breakdown: There is an important caveat
Carcinogenesis, Mutagenesis, Impairment of Fertility Long-term studies in animals to evaluate carcinogenic potential have not been done
The microdose case is best framed as metabolic or maintenance translation, not proven 72-week obesity dosing
In laboratory settings it functions as a carrier medium whose buffering-neutral, low-ionic composition facilitates dissolution of peptide and small-molecule powders for in vitro and model-system handling
B12 injection vs oral supplement , which fits you