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Chronic pain in patients with the hypermobility type of EhlersDanlos syndrome: evidence for generalized hyperalgesia

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An old study in 2006 investigated endogenous testosterone levels and smoking in males

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The discreetly high incidence of chronic fatigue observed in our cEDS cohort is in line with previous observations that emphasized that in EDS this issue is more common than in the general population and likely contributes to the patients functional impairment, psychological distress, and decreased QoL [86,87,88,89]