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Many smokers, however, block the holes with their lips or their fingers to obtain undiluted smoke with a higher concentration of nicotine (Kozlowski et al., 1980)

One example of this is the EU Tobacco Products Directive (TPD) , which has greatly influenced the world of nicotine products

Supporters of the law said it aims to deter adolescents from the harmful, sometimes fatal effects of nicotine addiction

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Saliva fights back against these bad breath invaders

Independent in vitro studies suggest that e-cigarette aerosol results in a dysfunctional immune response against both viral pathogens such as influenza A, human rhinovirus and respiratory syncytial virus, as well as bacterial pathogens such as Streptococcus pneumoniae, Staphylococcus aureus and Klebsiella pneumoniae (figure 3) [52, 53]