Smoking decreases sperm count, reduces motility and increases the number of abnormal sperm
Cell-cycle arrest and apoptosis of HCC1419 (mutp53Y220C) can be provoked by SLMP53-2, which is a new molecule to activate mutation of p53 by enhancing its interaction with the heat-shock protein 70 (Hsp70) and leading to the reestablishment of p53 DNA-binding ability as well as wild-type p53 144,145
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Relative to commonly used thresholds of reliability, these results would be considered almost perfect (Landis and Koch 1977)
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