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This information comes from the 2021 National Health Interview Survey (NHIS), which also looked at how common it is for people to use five different tobacco products: cigarettes, e-cigarettes, cigars, pipes, and smokeless tobacco

E-cigarette vapor has far fewer chemicals, but does contain potentially harmful metals like lead, volatile organic compounds and cancer-causing agents, according to the Centers for Disease Control and Prevention (CDC)

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Nicotine profoundly disrupts the sleep-wake cycle by altering the activity of neurotransmitters such as acetylcholine, dopamine, and norepinephrine, which regulate arousal and the brain's reward systems