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I appreciate those arguments but then, the anti-tobacco brigade seems oddly unwilling to support harm reduction for tobacco when it comes to less smokey nicotine-delivery mechanisms

doi:10 } : Cite journal requires |journal= (help) "Mortality from Smoking in Developed Countries 19502000: indirect estimates from national vital statistics" (PDF)

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Factor bioavailability from the table above and start low, adjusting based on body weight and tolerance

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