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In a comparative study, repeated exposure of human gingival fibroblasts to CS condensate or to nicotine-rich or nicotine-free e-vapour condensates led to alterations in morphology, suppression of proliferation and induction of apoptosis, with changes in all three parameters greater in cells exposed to CS condensate [29]

[216] The bill was approved by Parliament on 22 April 2026 and received royal assent on 29 April 2026 as the Tobacco and Vapes Act 2026

However, Americans growing interest in hygiene also played a significant role

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