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As the encephalopathy progresses, people experience more severe symptoms

and "complex aphthae", accounting for 5% of cases, where ulcers may be present on the genital mucosa in addition to mouth, healing is slower and pain is more severe

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National Youth Tobacco Survey, which included thousands of middle and high school students

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In a puncture-induced IVDD rat model, salidroside-induced upregulation of Parkin activated mitophagy to protect NP cells from apoptosis, which significantly ameliorated the progression of IVDD [90] (Fig