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The DSM-5 (Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition) identifies tobacco use disorder with criteria including cravings, difficulty reducing usage, and withdrawal symptoms like anxiety and restlessness when nicotine intake is reduced
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[2] The earliest known illustration of a cigar box instrument is an etching copyrighted in 1876 of two American Civil War soldiers at a campsite, one of whom is playing a cigar box fiddle
Research suggests that children and teenagers may be particularly sensitive to pure nicotine, making it less complicated for them to develop a cigarette use disorder
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