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Now it gets interesting: The tar poisons the lungs and must therefore be removed

In severe cases, it can cause shock and even death if its not immediately treated with a drug called epinephrine

Circulation 107 , 12281230 (2003)

In 1967, the Germans were the first to examine the relationship between nicotine and gastrointestinal disease after observing an increase in peptic ulcers in rats due to nicotine's increased gastric juice output