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Maines flavored cigar policy states that a cigar is deemed to have a characterizing flavor if the cigar is advertised or marketed as having or producing the taste or aroma of candy, chocolate, vanilla, fruit, berry, nut, herb, spice, honey, or an alcoholic drink

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Under the same inclusion criteria, we also extracted an independent list of genes from buccal cells (Supplementary Table S3) to validate the pathways identified from the blood samples

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