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The study simulated the type of nicotine exposure that occurs with smoking a hookah, which the researchers verified by measuring the levels of cotinine, the nicotine metabolite

Furthermore, apical dendritic spine complexity on pyramidal cells is significantly reduced in the CA3 region, while dendritic spine density is increased on basal and terminal pyramidal cell dendrites, DG basal granule dendrites, and CA1 basal pyramidal cell dendrites (Zeid et al., 2018)

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