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Validation of the 3D reconstructed human skin Comet assay, an animal-free alternative for following-up positive results from standard in vitro genotoxicity assays

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In a recent study, human blood neutrophils were stimulated with phorbol ester (PMA for phorbol-12-myristate-13-acetate, a compound known for its ability to stimulate NETosis) in the presence or absence of cigarette smoke condensate (CSC)

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