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Nicotine exposure gives rise to differential gene expression of endothelial cells, growth of atherosclerotic plaques, and angiogenesis [111, 112]

35 Regardless, the American Academy of Pediatrics recommends off-label NRT for youth who are moderately or severely addicted to nicotine because NRT is considered safer than continued cigarette and/or e-cigarette use

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"Biology of the Cabbage Looper on Tobacco In North Carolina1"

Tobacco promotion and the initiation of tobacco use: assessing the evidence for causality