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(2021) reported lower Clostridium group IV in PD as well as no strongly associated taxa with levodopa (L-DOPA) use, although preliminary data suggest Clostridium cluster IV may be linked to short-term motor-symptom response to L-DOPA, which deserves a thorough controlled validation

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Factors such as a disrupted gut microbiome and underlying infections, nutrient deficiencies such as magnesium, calcium and vitamin D as well as food sensitivities can cause joint and muscle pain in those with hyperthyroidism

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