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PMC 6204412

To counteract oxidative damage, cells activate the transcription factor NRF2 (nuclear factor erythroid related factor 2), which regulates antioxidant and detoxifying genes, such as NQO1 and HO-1 1

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The appearance goes against the presenter's clean-living public image which helped her secure her role on This Morning for many years up until her departure

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These factors contribute to a downward spiral in mitochondrial function and have been implicated in a number of chronic and age-related diseases