Firstly, upon contact with target cells, CTLs trigger degranulation, releasing perforin, which forms membrane channels in target cells, facilitating the entry of effector molecules such as granzymes, TNF, and secretory ATP, ultimately leading to target cell death
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Lindquist KA, Wager TD, Kober H, Bliss-Moreau E, Barrett LF
GATC works on the development, ratification, and implementation of the international treaty, the World Health Organization (WHO) Framework Convention on Tobacco Control (FCTC)
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