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70 HP 150 5-AMINO-1MQ Small-molecule NNMT inhibitor body-composition research ALIASES 5A1MQ, 5-amino-1-methylquinolinium iodide, NNMT inhibitor CLASS Small-molecule NNMT inhibitor (not a peptide) FORMULA C10H11IN2 HALF-LIFE Short plasma half-life (oral bioavailable) ROUTES Oral (in animal studies) Subcutaneous (research) MECHANISM OF ACTION 5-Amino-1-methylquinolinium iodide

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3,4 Physicians are excited to finally offer a treatment plan other than lifestyle changes 5,6,7 and intravitreal injections of pegcetacoplan (SYFOVRE, Apellis) or avacincaptad pegol (IZERVAY, Astellas Pharma)

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Inability to self-administer the intranasal spray, except with assistance from a spouse or home care nurse