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This was established as an important research question to be funded as part of the James Lind Alliance priority-setting partnership with the Pernicious Anaemia Society
Intention-to-treat is defined as the participant is placed in the treatment group he or she had been randomised to
doi:10.1016/S0026-0495(96)90171-7
This is due to the presence of intrinsic factor, a glycoprotein in the digestive tract that limits the bioavailability of B12
Vitamin B12 deficiency If left untreated, vitamin B deficiency can harm your brain and nervous system, leading to issues such as: Incontinence (not being able to control your pee or poop) Nerve issues, such as numbness, weakness, or nerve pain Erectile dysfunction (not being able to get an erect penis) Paralysis (not being able to move your body) Memory loss Paranoia (feeling like others are trying to hurt you) If you dont have symptoms but are at risk of low B12 levels, your doctor might also want you to have regular tests
The food factor BAC tool at CalculateBAC.com is specifically built to reduce this inaccuracy
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