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Neither age nor sex was associated with conversion (HR age = 0.96, 95% CI [0.911.02], P = 0.211
Nicotine is the addictive substance in tobacco and is as addictive as heroin or cocaine
There have been studies that have shown that nicotine is capable of altering the signal system of the brain mainly in the dopaminergic, cholinergic, and glutamatergic neurotransmitter systems, they explain
We compared baseline symptom severity among CHR with current co-use, tobacco use only or cannabis use only, other substance use, and no substance use from the North American Prodrome Longitudinal Study (NAPLS2), a multisite prospective study of individuals at risk for psychosis and healthy controls who underwent neuroimaging and clinical characterization then were followed for two years for development of a psychotic disorder (that is, conversion to psychosis)
Patients with SCZ have a high rate of smoking compared to the general population 9